Percutaneous closure of a patent foramen ovale after cryptogenic stroke
نویسندگان
چکیده
A patent foramen ovale is a common intracardiac finding that is located between the left and right atrium. It can cause right-to-left shunting and has a high prevalence in patients who suffer a cryptogenic stroke. Earlier trials did not show superiority of percutaneous patent foramen ovale closure with standard medical therapy over standard medical therapy alone in the treatment of cryptogenic stroke. Interestingly, several meta-analyses show positive results regarding closure, suggesting underpowering of the individual trials. Recently, two large prospective trials and one long-term follow-up study showed benefit of percutaneous closure over standard medical therapy in treatment of cryptogenic stroke. A larger right-to-left shunt or the presence of an atrial septal aneurysm were predictors for a recurrent event. Therefore, percutaneous patent foramen ovale closure after cryptogenic stroke should be recommended over antiplatelet therapy alone in patients younger than 55 years of age with a high-risk patent foramen ovale.
منابع مشابه
Ischemic Stroke in Patients with Percutaneous Patent Foramen Ovale Closure
Background: The prevalence of patent foramen ovale is approximately 50% in patients who have suffered a cryptogenic stroke. The recurrence of ischemic stroke after percutaneous patent foramen ovale closure is approximately 1% per year. Objective: The aim of this study was to evaluate the prevalence of recurrent ischemic stroke in our population undergoing percutaneous patent foramen ovale closu...
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Current indications for percutaneous closure of patent foramen ovale.
Patent foramen ovale (PFO) occurs when the septum primum and secundum fail to fuse after birth. A quarter of adults have this defect, which is usually an incidental finding with no clinical repercussions. However, the presence of PFO has been associated with a range of clinical conditions such as cryptogenic stroke, migraine, platypnea-orthodeoxia syndrome, and decompression illness. Cryptogeni...
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Percutaneous closure of patent foramen ovale (PFO) has been proposed as a therapeutic option for cryptogenic stroke. The aim of this article was to describe the experience with this treatment at our center. Up until February 2006, percutaneous closure of PFO was carried out in 52 patients who presented with one or more cryptogenic strokes or transient ischemic attacks. The procedure was carried...
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